anti-TIMM44 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG42907
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes TIMM44 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TIMM44 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 153-452 of Human TIMM44 (NP_006342.2). |
| 偶联标记 | Un-conjugated |
| 別名 | Mitochondrial import inner membrane translocase subunit TIM44; TIM44 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Rat kidney | ||||||
| 实际分子量 | ~ 47 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TIMM44 |
| 全名 | translocase of inner mitochondrial membrane 44 homolog (yeast) |
| 背景介绍 | This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma. [provided by RefSeq, Jul 2016] |
| 生物功能 | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source. [UniProt] |
| 细胞定位 | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Mitochondrion matrix. [UniProt] |
| 预测分子量 | 51 kDa |
检测图片 (2)
ARG42907 anti-TIMM44 antibody ICC/IF image
Immunofluorescence: L929 cells stained with ARG42907 anti-TIMM44 antibody at 1:100 dilution.
ARG42907 anti-TIMM44 antibody WB image
Western blot: 25 µg of Rat kidney lysate stained with ARG42907 anti-TIMM44 antibody at 1:1000 dilution.
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