anti-TLN1 / Talin 1 antibody [TA205]
![anti-TLN1 / Talin 1 antibody [TA205]](/upload/image/products/ARG23092_FACS_1_210_205.jpg)
![anti-TLN1 / Talin 1 antibody [TA205]](/upload/image/products/ARG23092_FACS_1.jpg)
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- 克隆:
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- 靶点名称:
- 抗原物种:
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CAT.NO. : ARG23092
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [TA205] recognizes TLN1 / Talin 1 Mouse anti Human Talin antibody, clone TA205 recognizes human talin, a ~225 kDa cytoskeletal protein. Mouse anti Human Talin antibody, clone TA205 may be used to stain adhesion plaques in fixed and permeabilized fibroblasts. Mouse anti Human Talin antibody, clone recognizes an epitope between residues 139 and 433. |
|---|---|
| 反应物种 | Hu, Chk, Rb |
| 应用 | FACS, ICC/IF, IHC-Fr, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | TA205 |
| 同位型 | IgG1 |
| 靶点名称 | TLN1 / Talin 1 |
| 抗原物种 | Human |
| 抗原 | Human platelet talin. |
| 偶联标记 | Un-conjugated |
| 別名 | Talin-1; TLN; ILWEQ |
应用说明
| 应用建议 |
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| 应用说明 | FACS: Membrane permeabilization is required for this application. Use 10 µl of the suggested working dilution to label 10^6 cells. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% Sodium azide |
| 抗菌剂 | 0.09% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TLN1 |
| 全名 | talin 1 |
| 背景介绍 | This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009] |
| 生物功能 | Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts (By similarity). [UniProt] |
| 预测分子量 | 270 kDa |
检测图片 (1)
ARG23092 anti-TLN1 / Talin 1 antibody [TA205] FACS image
Flow Cytometry: Human peripheral blood platelets stained with ARG23092 anti-TLN1 / Talin 1 antibody [TA205].
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