anti-TMPO / Lap2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes TMPO / Lap2
  • 反应物种: Hu, Ms
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: TMPO / Lap2
  • 抗原物种: Human
  • 抗原: Synthetic peptide corresponding to aa. 1-50 of Human TMPO / Lap2.
  • Brand:
CAT.NO. : ARG66408
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes TMPO / Lap2
反应物种Hu, Ms
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称TMPO / Lap2
抗原物种Human
抗原Synthetic peptide corresponding to aa. 1-50 of Human TMPO / Lap2.
偶联标记Un-conjugated
別名Splenin; Lamina-associated polypeptide 2, isoform alpha; Thymopoietin isoform alpha; PRO0868; CMD1T; LAP2; TP; TP5; TP alpha; Thymopoietin-related peptide isoform alpha; LEMD4; TPRP isoform alpha
应用说明
应用建议
应用推荐稀释比
IHC-P1:100 - 1:300
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量~ 50 kDa, 80 kDa
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 21917 Mouse TMPO

GeneID: 7112 Human TMPO

Swiss-port # P42166 Human Lamina-associated polypeptide 2, isoform alpha

Swiss-port # Q61029 Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma

基因名称TMPO
全名thymopoietin
背景介绍The protein encoded by this gene resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in this gene are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, May 2010]
生物功能May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Plays an important role, together with LMNA, in the nuclear anchorage of RB1.

TP and TP5 may play a role in T-cell development and function. TP5 is an immunomodulating pentapeptide. [UniProt]
细胞定位Nucleus. Chromosome. Note=Expressed diffusely throughout the nucleus. [UniProt]
预测分子量75 kDa
翻译后修饰Mitosis-specific phosphorylation specifically abolishes its binding to lamin B and chromosomes.

Citrullinated by PADI4. [UniProt]
检测图片 (5)
  • ARG66408 anti-TMPO / Lap2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human cervical cancer stained with ARG66408 anti-TMPO / Lap2 antibody at 1:200 dilution.

  • ARG66408 anti-TMPO / Lap2 antibody WB image

    Western blot: Mouse kidney and HepG2 lysates stained with ARG66408 anti-TMPO / Lap2 antibody at 1:800 dilution.

  • ARG66408 anti-TMPO / Lap2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human cervical cancer stained with ARG66408 anti-TMPO / Lap2 antibody at 1:200 dilution.

  • ARG66408 anti-TMPO / Lap2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human liver stained with ARG66408 anti-TMPO / Lap2 antibody at 1:200 dilution.

  • ARG66408 anti-TMPO / Lap2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human liver stained with ARG66408 anti-TMPO / Lap2 antibody at 1:200 dilution.

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