anti-TMPRSS3 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes TMPRSS3
  • 反应物种: Hu
  • 预测物种: Ms
  • 应用: WB
  • 特异性: This antibody is expected to recognise all four reported isoforms (NP_076927.1; NP_115777.1; NP_115780.1; NP_115781.1)
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: TMPRSS3
  • Brand:
CAT.NO. : ARG64377
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes TMPRSS3
反应物种Hu
预测物种Ms
应用WB
特异性This antibody is expected to recognise all four reported isoforms (NP_076927.1; NP_115777.1; NP_115780.1; NP_115781.1)
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称TMPRSS3
抗原物种Human
抗原C-EKIVYHSKYKPKR
偶联标记Un-conjugated
別名ECHOS1; Transmembrane protease serine 3; DFNB10; Tumor-associated differentially-expressed gene 12 protein; DFNB8; TADG12; EC 3.4.21.-; Serine protease TADG-12
应用说明
应用建议
应用推荐稀释比
WB0.1 - 0.3 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 64699 Human TMPRSS3

Swiss-port # P57727 Human Transmembrane protease serine 3

背景介绍This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]
研究领域Cell Biology and Cellular Response antibody; Neuroscience antibody
预测分子量49 kDa
翻译后修饰Undergoes autoproteolytic activation.
检测图片 (1)
  • ARG64377 anti-TMPRSS3 antibody WB image

    Western Blot: A431 cell lysate (35 µg protein in RIPA buffer) stained with ARG64377 anti-TMPRSS3 antibody at 0.1 µg/ml dilution.

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