anti-TNFRSF18 antibody [DTA-1]

Key features and details

  • 产品描述: Rat Monoclonal antibody [DTA-1] recognizes TNFRSF18
  • 反应物种: Ms
  • 应用: FACS, ICC/IF
  • 宿主: Rat
  • 克隆: Monoclonal
  • 克隆号: DTA-1
  • 同位型: IgG2b, lambda
  • 靶点名称: TNFRSF18
  • 抗原物种: Mouse
  • Brand:
CAT.NO. : ARG56104
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Product Details
概述
产品描述Rat Monoclonal antibody [DTA-1] recognizes TNFRSF18
反应物种Ms
应用FACS, ICC/IF
宿主Rat
克隆Monoclonal
克隆号DTA-1
同位型IgG2b, lambda
靶点名称TNFRSF18
抗原物种Mouse
抗原Mouse CD25+ CD4+ T cells.
偶联标记Un-conjugated
別名AITR; CD antigen CD357; Tumor necrosis factor receptor superfamily member 18; Glucocorticoid-induced TNFR-related protein; Gitr
应用说明
应用建议
应用推荐稀释比
FACS0.5 - 1 µg/10^6 cells in 0.1ml
ICC/IF0.5 - 1 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA
抗菌剂0.05% Sodium azide
稳定剂0.1 mg/ml BSA
浓度0.2 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 21936 Mouse TNFRSF18

Swiss-port # O35714 Mouse Tumor necrosis factor receptor superfamily member 18

基因名称Tnfrsf18
全名tumor necrosis factor receptor superfamily, member 18
背景介绍This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
生物功能Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway (By similarity). [UniProt]
细胞定位Secreted, cell surface
预测分子量26 kDa
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