anti-TNNI1 antibody [36E7]

CAT.NO. : ARG57012

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [36E7] recognizes TNNI1
反应物种	Hu
应用	WB
宿主	Mouse
克隆	Monoclonal
克隆号	36E7
同位型	IgG2b, kappa
靶点名称	TNNI1
抗原物种	Human
抗原	Recombinant fragment around aa. 1-187 of Human TNNI1.
偶联标记	Un-conjugated
別名	Troponin I, slow-twitch isoform; SSTNI; TNN1; Troponin I, slow skeletal muscle

应用说明

应用建议

应用	推荐稀释比
WB	1:500 - 1:5000

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 7135 Human TNNI1 Swiss-port # P19237 Human Troponin I, slow skeletal muscle
基因名称	TNNI1
全名	troponin I type 1 (skeletal, slow)
背景介绍	Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008]
生物功能	Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. [UniProt]
预测分子量	22 kDa

检测图片 (1)

ARG57012 anti-TNNI1 antibody [36E7] WB image
Western blot: 40 µg of Mouse muscle stained with ARG57012 anti-TNNI1 antibody [36E7] at 1) 1:500, 2) 1:1000, and, 3) 1:5000 dilution.

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