anti-TNXB antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes TNXB
  • 反应物种: Hu
  • 应用: IHC-P
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: TNXB
  • 抗原物种: Human
  • 抗原: Synthetic peptide of Human TNXB. (DLRAVAVSGLDPARKYKFLLFGLQNGKRH)
  • Brand:
CAT.NO. : ARG58135
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes TNXB
反应物种Hu
应用IHC-P
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称TNXB
抗原物种Human
抗原Synthetic peptide of Human TNXB. (DLRAVAVSGLDPARKYKFLLFGLQNGKRH)
偶联标记Un-conjugated
別名EDS3; Hexabrachion-like protein; XB; TNXB1; TNX; HXBL; TN-X; TENX; XBS; TNXBS; VUR8; TNXB2; Tenascin-X
应用说明
应用建议
应用推荐稀释比
IHC-P0.5 - 1 µg/ml
应用说明IHC-P: Antigen Retrieval: Boil tissue section in 10mM Citrate buffer (pH 6.0) for 20 min followed by cooling at RT.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS, 0.025% Sodium azide and 2.5% BSA.
抗菌剂0.025% Sodium azide
稳定剂2.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 7148 Human TNXB

Swiss-port # P22105 Human Tenascin-X

基因名称TNXB
全名tenascin XB
背景介绍This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能Appears to mediate interactions between cells and the extracellular matrix. Substrate-adhesion molecule that appears to inhibit cell migration. Accelerates collagen fibril formation. May play a role in supporting the growth of epithelial tumors. [UniProt]
细胞定位Cytoplasmic. [UniProt]
预测分子量458 kDa
检测图片 (1)
  • ARG58135 anti-TNXB antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human placenta stained with ARG58135 anti-TNXB antibody. Antigen Retrieval: Boil tissue section in 10mM Citrate buffer (pH 6.0) for 20 min followed by cooling at RT.

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