anti-TOX3 antibody [TOX3/1123]

CAT.NO. : ARG56189

US＄ Please choose

Size:

50 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [TOX3/1123] recognizes TOX3
反应物种	Hu
应用	WB
宿主	Mouse
克隆	Monoclonal
克隆号	TOX3/1123
同位型	IgG2b, kappa
靶点名称	TOX3
抗原物种	Human
抗原	A recombinant fragment (139 amino acid residues around aa 200-400) from the human TOX3 protein.
偶联标记	Un-conjugated
別名	Trinucleotide repeat-containing gene 9 protein; TNRC9; TOX high mobility group box family member 3; CAG trinucleotide repeat-containing gene F9 protein; CAGF9

应用说明

应用建议

应用	推荐稀释比
WB	1 - 2 µg/ml

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

阳性对照

A431

实际分子量

~ 53 kDa

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA.
抗菌剂	0.05% Sodium azide
稳定剂	0.1 mg/ml BSA
浓度	0.2 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 27324 Human TOX3 Swiss-port # O15405 Human TOX high mobility group box family member 3
基因名称	TOX3
全名	TOX high mobility group box family member 3
背景介绍	The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009]
生物功能	Transcriptional coactivator of the p300/CBP-mediated trancription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region. [UniProt]
细胞定位	Cytoplasmic & nuclear
预测分子量	63 kDa

检测图片 (1)

ARG56189 anti-TOX3 antibody [TOX3/1123] WB image
Western blot: A431 cell lysate stained with ARG56189 anti-TOX3 antibody [TOX3/1123].

New Products