anti-TRAF7 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes TRAF7
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: TRAF7
  • 抗原物种: Human
  • 抗原: Synthetic peptide of Human TRAF7.
  • Brand:
CAT.NO. : ARG40250
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes TRAF7
反应物种Hu, Ms, Rat
应用ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称TRAF7
抗原物种Human
抗原Synthetic peptide of Human TRAF7.
偶联标记Un-conjugated
別名E3 ubiquitin-protein ligase TRAF7; RING finger and WD repeat-containing protein 1; EC 6.3.2.-; RFWD1; RING finger protein 119; TNF receptor-associated factor 7; RNF119
应用说明
预测反应性说明Human
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Mouse fetal stomach
实际分子量65 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 84231 Human TRAF7

Swiss-port # Q6Q0C0 Human E3 ubiquitin-protein ligase TRAF7

基因名称TRAF7
全名TNF receptor-associated factor 7, E3 ubiquitin protein ligase
背景介绍Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.[supplied by OMIM, Apr 2004]
生物功能E3 ubiquitin ligase capable of auto-ubiquitination, following phosphorylation by MAP3K3. Potentiates MEKK3-mediated activation of the NF-kappa-B, JUN/AP1 and DDIT3 transcriptional regulators. Induces apoptosis when overexpressed. [UniProt]
细胞定位Cytoplasmic vesicle. [UniProt]
预测分子量75 kDa
翻译后修饰Phosphorylated by MAP3K3.

Ubiquitinates itself upon phosphorylation. [UniProt]
检测图片 (1)
  • ARG40250 anti-TRAF7 antibody WB image

    Western blot: 25 µg of Mouse fetal stomach lysate stained with ARG40250 anti-TRAF7 antibody.

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