anti-TRAM2 antibody
CAT.NO. : ARG59717
US$ Please choose
US$ Please choose
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概述
产品描述 | Rabbit Polyclonal antibody recognizes TRAM2 |
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反应物种 | Hu, Ms, Rat |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | TRAM2 |
抗原物种 | Human |
抗原 | Synthetic peptide derived from Human TRAM2. |
偶联标记 | Un-conjugated |
別名 | Translocating chain-associated membrane protein 2 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
实际分子量 | ~ 40 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q15035 Human Translocating chain-associated membrane protein 2 Swiss-port # Q924Z5 Mouse Translocating chain-associated membrane protein 2 |
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基因名称 | TRAM2 |
全名 | translocation associated membrane protein 2 |
背景介绍 | TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum (ER) membrane.[supplied by OMIM, Jul 2004] |
生物功能 | Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. [UniProt] |
细胞定位 | Membrane; Multi-pass membrane protein. [UniProt] |
预测分子量 | 43 kDa |
