anti-TREM1 antibody [6B1]
CAT.NO. : ARG43857
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概述
| 产品描述 | Mouse Monoclonal antibody recognizes TREM1. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 6B1 |
| 同位型 | IgG1 |
| 靶点名称 | TREM1 |
| 抗原物种 | Human |
| 抗原 | Human TREM1 recombinant protein. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Triggering receptor expressed on myeloid cells 1 |
| 別名 | TREM1; Triggering Receptor Expressed On Myeloid Cells 1; TREM-1; CD354; Triggering Receptor Expressed On Monocytes 1; CD354 Antigen |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein-A affinity chromatography |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | Protect from prolonged exposure to light. Do not freeze. |
生物信息
| 数据库连接 | Swiss-port # Q9NP99 Human Triggering receptor expressed on myeloid cells 1 |
|---|---|
| 基因名称 | TREM1 |
| 全名 | Triggering Receptor Expressed On Myeloid Cells 1 |
| 背景介绍 | This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
| 生物功能 | Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. [UniProt] |
| 细胞定位 | Cell membrane, Membrane, Secreted |
| 预测分子量 | 26 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein |
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