anti-TREM2 antibody [78.18]
![anti-TREM2 antibody [78.18]](/upload/image/products/ARG23873_FACS_1_210_205.jpg)
![anti-TREM2 antibody [78.18]](/upload/image/products/ARG23873_FACS_1.jpg)
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- 抗原物种:
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Brand:
CAT.NO. : ARG23873
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Product Details
概述
| 产品描述 | Rat Monoclonal antibody [78.18] recognizes TREM2 |
|---|---|
| 反应物种 | Ms |
| 应用 | FACS |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 78.18 |
| 同位型 | IgG1 |
| 靶点名称 | TREM2 |
| 抗原物种 | Mouse |
| 抗原 | Mouse TREM-2 Fc fusion protein. |
| 偶联标记 | Un-conjugated |
| 別名 | Trem2a; Trem2b; TREM-2; Triggering receptor expressed on myeloid cells 2; Triggering receptor expressed on monocytes 2; Trem2c |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | FACS: Use 10 µl of the suggested working dilution to label 1x10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% Sodium azide. |
| 抗菌剂 | 0.09% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q99NH8 Mouse Triggering receptor expressed on myeloid cells 2 |
|---|---|
| 基因名称 | TREM2 |
| 全名 | triggering receptor expressed on myeloid cells 2 |
| 背景介绍 | This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012] |
| 生物功能 | May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells. [UniProt] |
| 细胞定位 | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 3: Secreted. [UniProt] |
| 预测分子量 | 25 kDa |
检测图片 (1)
ARG23873 anti-TREM2 antibody [78.18] FACS image
Flow Cytometry: Mouse TREM2 transfected cells stained with ARG23873 anti-TREM2 antibody [78.18], followed by incubation with RPE labelled secondary antibody.
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