anti-TRIB2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes TRIB2
  • 反应物种: Hu, Ms, Rat
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: TRIB2
  • 抗原物种: Human
  • 抗原: Synthetic peptide corresponding to aa. 175-211 of Human TRIB2. (DLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSD)
  • Brand:
CAT.NO. : ARG43044
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes TRIB2
反应物种Hu, Ms, Rat
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称TRIB2
抗原物种Human
抗原Synthetic peptide corresponding to aa. 175-211 of Human TRIB2. (DLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSD)
偶联标记Un-conjugated
別名TRB-2; GS3955; Tribbles homolog 2; C5FW; TRB2
应用说明
应用建议
应用推荐稀释比
IHC-P1:200 - 1:1000
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 5% BSA.
抗菌剂0.05% Sodium azide
稳定剂5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 217410 Mouse TRIB2

GeneID: 28951 Human TRIB2

Swiss-port # Q8K4K3 Mouse Tribbles homolog 2

Swiss-port # Q92519 Human Tribbles homolog 2

基因名称TRIB2
全名tribbles pseudokinase 2
背景介绍This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
生物功能Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity (By similarity). [UniProt]
细胞定位Cytoplasm. Cytoplasm, cytoskeleton. Note=May associate with the cytoskeleton. [UniProt]
预测分子量39 kDa
检测图片 (4)
  • ARG43044 anti-TRIB2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human tonsil tissue stained with ARG43044 anti-TRIB2 antibody at 1 µg/ml dilution.

  • ARG43044 anti-TRIB2 antibody WB image

    Western blot: SW620 whole cell lysate stained with ARG43044 anti-TRIB2 antibody at 0.5 µg/ml dilution.

  • ARG43044 anti-TRIB2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat spleen tissue stained with ARG43044 anti-TRIB2 antibody at 1 µg/ml dilution.

  • ARG43044 anti-TRIB2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse spleen tissue stained with ARG43044 anti-TRIB2 antibody at 1 µg/ml dilution.

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