anti-TRPC4AP antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG64957
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes TRPC4AP |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 特异性 | This antibody is expected to recognize both reported isoforms (NP_955400.1; NP_056453.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TRPC4AP |
| 抗原物种 | Human |
| 抗原 | C-KLTQETTYPNTYIFD |
| 偶联标记 | Un-conjugated |
| 別名 | TRRP4AP; PPP1R158; Trpc4-associated protein; Protein TRUSS; C20orf188; Protein TAP1; Short transient receptor potential channel 4-associated protein; Trp4-associated protein; TNF-receptor ubiquitous scaffolding/signaling protein; TRUSS |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q8TEL6 Human Short transient receptor potential channel 4-associated protein |
|---|---|
| 基因名称 | TRPC4AP |
| 全名 | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| 生物功能 | Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1. [UniProt] |
| 研究领域 | Gene Regulation antibody; Signaling Transduction antibody |
| 预测分子量 | 91 kDa |
检测图片 (1)
ARG64957 anti-TRPC4AP antibody WB image
Western Blot: U937 lysate (35 µg protein in RIPA buffer) stained with ARG64957 anti-TRPC4AP antibody at 1 µg/ml dilution.
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