anti-TRPC7 antibody [S64A-36]
CAT.NO. : ARG22233
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概述
| 产品描述 | Mouse Monoclonal antibody [S64A-36] recognizes TRPC7 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC, IP, WB |
| 特异性 | Detects ~100kDa. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | S64A-36 |
| 同位型 | IgG1 |
| 靶点名称 | TRPC7 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around aa. 845-862 of Human TrpC7 |
| 偶联标记 | Un-conjugated |
| 別名 | hTRP7; Transient receptor protein 7; TrpC7; Short transient receptor potential channel 7; TRP-7; TRP7 |
应用说明
| 应用建议 |
| ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q9HCX4 Human Short transient receptor potential channel 7 Swiss-port # Q9WVC5 Mouse Short transient receptor potential channel 7 |
|---|---|
| 基因名称 | TRPC7 |
| 全名 | transient receptor potential cation channel, subfamily C, member 7 |
| 生物功能 | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion. [UniProt] |
| 细胞定位 | Membrane |
| 预测分子量 | 100 kDa |
| 翻译后修饰 | Phosphorylation by PRKG1 at Thr-15 negatively regulates TRPC7 activity. |
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