anti-TRPM7 / LTRPC7 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes TRPM7 / LTRPC7
  • 反应物种: Hu, Ms
  • 预测物种: Dog, Rat, Pig
  • 应用: ICC/IF, IHC-P
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: TRPM7 / LTRPC7
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG63144
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes TRPM7 / LTRPC7
反应物种Hu, Ms
预测物种Dog, Rat, Pig
应用ICC/IF, IHC-P
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称TRPM7 / LTRPC7
抗原物种Human
抗原C-TKESESTNSVRLML
偶联标记Un-conjugated
別名Transient receptor potential cation channel subfamily M member 7; CHAK; ALSPDC; LTrpC7; LTRPC7; CHAK1; Channel-kinase 1; TRP-PLIK; EC 2.7.11.1; LTrpC-7; Long transient receptor potential channel 7
应用说明
应用建议
应用推荐稀释比
ICC/IF10 µg/ml
IHC-P4 - 6 µg/ml
应用说明IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 54822 Human TRPM7

GeneID: 58800 Mouse TRPM7

Swiss-port # Q923J1 Mouse Transient receptor potential cation channel subfamily M member 7

Swiss-port # Q96QT4 Human Transient receptor potential cation channel subfamily M member 7

背景介绍The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam.[provided by RefSeq, May 2010]
研究领域Neuroscience antibody
预测分子量213 kDa
翻译后修饰Autophosphorylated.
检测图片 (2)
  • ARG63144 anti-TRPM7 / LTRPC7 antibody ICC/IF image

    Immunofluorescence: Paraformaldehyde fixed U2OS cells permeabilized with 0.15% Triton. Cells were stained with ARG63144 anti-TRPM7 / LTRPC7 antibody (green) at 10 µg/ml dilution for 1 hour. DAPI (blue) for nuclear staining. Phalloidin (red) for Actin filaments staining. Negative control: Unimmunized goat IgG (green) at 10 µg/ml dilution.

  • ARG63144 anti-TRPM7 / LTRPC7 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Mouse Hippocampus. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63144 anti-TRPM7 / LTRPC7 antibody at 4 µg/ml dilution followed by HRP-staining. Similar results were obtained after antigen retrieval at pH9.

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