anti-TWF2 antibody
CAT.NO. : ARG40044
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概述
产品描述 | Rabbit Polyclonal antibody recognizes TWF2 |
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反应物种 | Hu, Ms, Rat |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | TWF2 |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 1-369 of Human TWF2 (NP_009215.1). |
偶联标记 | Un-conjugated |
別名 | A6-related protein; Protein tyrosine kinase 9-like; Twinfilin-2; PTK9L; A6r; MSTP011; A6RP; Twinfilin-1-like protein; hA6RP |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | Mouse thymus and 293T | ||||
实际分子量 | 40 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | TWF2 |
全名 | twinfilin actin binding protein 2 |
背景介绍 | The protein encoded by this gene was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin (PTK9), a conserved actin monomer-binding protein. [provided by RefSeq, Jul 2008] |
生物功能 | Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia (By similarity). [UniProt] |
细胞定位 | Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell projection, stereocilium. Note=Perinuclear and G-actin-rich cortical actin structure sublocalization. [UniProt] |
预测分子量 | 40 kDa |
翻译后修饰 | In vitro, phosphorylated by PRKCZ, CK2 and SRC. [UniProt] |
检测图片 (2)
ARG40044 anti-TWF2 antibody WB image
Western blot: 25 µg of Mouse thymus and 293T cell lysates stained with ARG40044 anti-TWF2 antibody at 1:1000 dilution.
ARG40044 anti-TWF2 antibody IP image
Immunoprecipitation: 200 µg extracts of 293T cells immunoprecipitated and stained with ARG40044 anti-TWF2 antibody at 1:1000 dilution.
