anti-TXNDC4 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
Product Details
| 产品描述 | Rabbit Polyclonal antibody recognizes TXNDC4 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TXNDC4 |
| 抗原物种 | Human |
| 抗原 | Fusion protein of Human TXNDC4. |
| 偶联标记 | Un-conjugated |
| 別名 | Thioredoxin domain-containing protein 4; ERp44; Endoplasmic reticulum resident protein 44; PDIA10; TXNDC4; ER protein 44 |
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | WB: 231, HeLa, HepG2, A431, K562 and Raji IHC-P: Human thyroid cancer and Human prostate cancer | ||||||
| 实际分子量 | ~ 47 kDa |
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 40% Glycerol |
| 浓度 | 0.4 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | Swiss-port # Q9BS26 Human Endoplasmic reticulum resident protein 44 |
|---|---|
| 基因名称 | ERP44 |
| 全名 | endoplasmic reticulum protein 44 |
| 背景介绍 | This gene encodes a member of the protein disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins. It has an inferred N-terminal signal peptide, a catalytically active thioredoxin (TRX) domain, two TRX-like domains and a C-terminal ER-retention sequence. This protein functions as a pH-regulated chaperone of the secretory pathway and likely plays a role in protein quality control at the endoplasmic reticulum - Golgi interface. [provided by RefSeq, Dec 2016] |
| 生物功能 | Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum. [UniProt] |
| 细胞定位 | Endoplasmic reticulum lumen. [UniProt] |
| 预测分子量 | 47 kDa |
ARG42756 anti-TXNDC4 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human thyroid cancer tissue stained with ARG42756 anti-TXNDC4 antibody (left) at 1:30 dilution, or the same antibody pre-incubated with fusion protein (right). (Original magnification: X200).
ARG42756 anti-TXNDC4 antibody WB image
Western blot: 40 µg of 231, HeLa, HepG2, A431, K562 and Raji cell lysates stained with ARG42756 anti-TXNDC4 antibody at 1:400 dilution.
ARG42756 anti-TXNDC4 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human prostate cancer tissue stained with ARG42756 anti-TXNDC4 antibody (left) at 1:30 dilution, or the same antibody pre-incubated with fusion protein (right). (Original magnification: X200).
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