anti-Tyrosine Hydroxylase antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Tyrosine Hydroxylase
  • 反应物种: Hu, Ms, Rat, Mamm
  • 应用: ICC/IF, IHC-Fr, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Tyrosine Hydroxylase
  • 抗原物种: Rat
  • 抗原: SDS-denatured rat tyrosine hydroxylase purified from pheochromocytoma
  • Brand:
CAT.NO. : ARG52461
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Tyrosine Hydroxylase
反应物种Hu, Ms, Rat, Mamm
应用ICC/IF, IHC-Fr, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Tyrosine Hydroxylase
抗原物种Rat
抗原SDS-denatured rat tyrosine hydroxylase purified from pheochromocytoma
偶联标记Un-conjugated
別名DYT14; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH; DYT5b; EC 1.14.16.2
应用说明
应用建议
应用推荐稀释比
ICC/IF1:1000
IHC-Fr1:1000
IHC-P1:500 - 1:1500
WB1:1000
应用说明Specific for the ~60k tyrosine hydroxylase protein.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity Purified
缓冲液10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
稳定剂0.1 mg/ml BSA, 50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 21823 Mouse TH

GeneID: 25085 Rat TH

GeneID: 7054 Human TH

基因名称TH
全名tyrosine hydroxylase
背景介绍Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000; Salvatore et al., 2001; Dunkley et al., 2004).
产品亮点Related Antibody Duos and Panels:
ARG30212 Phospho Tyrosine Hydroxylase Antibody Panel (Total, pS31, pS40)
Related products:
Tyrosine Hydroxylase antibodies; Tyrosine Hydroxylase Duos / Panels; Anti-Rabbit IgG secondary antibodies;
Related news:
Astrocyte-to-neuron conversion for Parkinson's disease treatment
研究领域Cancer antibody; Metabolism antibody; Neuroscience antibody
预测分子量59 kDa
检测图片 (4)
  • ARG52461 anti-Tyrosine Hydroxylase antibody WB image

    Western blot: 30 µg of Mouse brain tissue lysate stained with ARG52461 anti-Tyrosine Hydroxylase antibody at 1:500 dilution.

  • ARG52461 anti-Tyrosine Hydroxylase antibody ICC/IF image

    Immunofluorescence: E17 Rat midbrain mixed neuronal cultures stained with ARG52461 anti-Tyrosine Hydroxylase antibody (green) and ARG52328 anti-MAP2 antibody (red).

  • ARG52461 anti-Tyrosine Hydroxylase antibody IHC-Fr image

    Immunohistochemistry: Frozen section of Mouse brain stained with ARG52461 anti-Tyrosine Hydroxylase antibody at 1:1000 dilution.

  • ARG52461 anti-TH antibody WB image

    Western Blot: 10 μg of rat caudate lysate showing specific immunolabeling of the ~60k TH protein stained with TH antibody (ARG52461).

参考文献

Downregulated Calcium-Binding Protein S100A16 and HSP27 in Placenta-Derived Multipotent Cells Induce Functional Astrocyte Differentiation

Imaging Cytometry / Human

Yu-Che Cheng et al.
Stem Cell Rev Rep.,  (2022)

publication_link

 

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