anti-UBR1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 偶联标记:
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Brand:
CAT.NO. : ARG44982
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody recognizes UBR1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG |
| 靶点名称 | UBR1 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | UBR1; Ubiquitin Protein Ligase E3 Component N-Recognin1; Ubiquitin-Protein Ligase E3-Alpha-1; Ubiquitin-Protein Ligase E3-Alpha-I; E3 Ubiquitin-Protein Ligase UBR1; N-Recognin-1; RING-Type E3 Ubiquitin Transferase UBR1; Ubiquitin-Protein Ligase E3-Alpha; Ubiquitin Ligase E3 Alpha-I; EC2.3.2.27; E3a Ligase; JBS |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | UBR1 |
| 全名 | Ubiquitin Protein Ligase E3 Component N-Recognin1 |
| 背景介绍 | The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul2008] |
| 生物功能 | Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth. [Uniprot] |
| 细胞定位 | Cytoplasm. [Uniprot] |
| 翻译后修饰 | Acetylation, Phosphoprotein. [Uniprot] |
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