anti-UBR7 antibody

Key features and details

  • 产品描述: Mouse Monoclonal antibody recognizes UBR7
  • 反应物种: Hu
  • 应用: IHC-P, IP, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 同位型: IgG2a
  • 靶点名称: UBR7
  • 抗原物种: Human
  • 抗原表位: YPDPEDEIPD EMIQCVVCED WFHGRHLGAI PPESGDFQEM VCQACMKRCS FLWAYAAQLA VTKISTEDDG LVRNIDGIGD QEVIKPENGE HQDSTLKEDV PEQGKDDVRE VKVEQNSEPC AGSSSESDLQ TVFKNESLNA ESKSGCKLQE LKAKQLIKKD TATYWPLNWR SKLCTCQDCM KMYGDLDVLF LTDEYDTVLA YENKGKIAQA TDRSDPLMDT LSSMNRVQQV ELICEYNDLK TELKDYLKRF ADEGTVVKRE DIQQFFEEFQ SKKRRRVDGM
  • Brand:
CAT.NO. : ARG44983
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Product Details
概述
产品描述Mouse Monoclonal antibody recognizes UBR7
反应物种Hu
应用IHC-P, IP, WB
宿主Mouse
克隆Monoclonal
同位型IgG2a
靶点名称UBR7
抗原物种Human
抗原表位YPDPEDEIPD EMIQCVVCED WFHGRHLGAI PPESGDFQEM VCQACMKRCS FLWAYAAQLA VTKISTEDDG LVRNIDGIGD QEVIKPENGE HQDSTLKEDV PEQGKDDVRE VKVEQNSEPC AGSSSESDLQ TVFKNESLNA ESKSGCKLQE LKAKQLIKKD TATYWPLNWR SKLCTCQDCM KMYGDLDVLF LTDEYDTVLA YENKGKIAQA TDRSDPLMDT LSSMNRVQQV ELICEYNDLK TELKDYLKRF ADEGTVVKRE DIQQFFEEFQ SKKRRRVDGM
偶联标记Un-conjugated
別名UBR7; Ubiquitin Protein Ligase E3 Component N-Recognin7; C14orf130; Ubiquitin Protein Ligase E3 Component N-Recognin7 (Putative); Putative E3 Ubiquitin-Protein Ligase UBR7; RING-Type E3 Ubiquitin Transferase UBR7; N-Recognin-7; Chromosome14 Open Reading Frame130; EC2.3.2.27; LICAS
应用说明
应用建议
应用推荐稀释比
IHC-P1:1000
IP1:100
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Protein A purification
缓冲液PBS with0.09% sodium azide
抗菌剂0.09% sodium azide
存放说明For continuous use, store undiluted antibody at2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 55148 Human UBR7

Swiss-port # Q8N806 Human Putative E3 ubiquitin-protein ligase UBR7

基因名称UBR7
全名Ubiquitin Protein Ligase E3 Component N-Recognin7
背景介绍This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome. [provided by RefSeq, Jul2016]
生物功能E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. [Uniprot]
翻译后修饰Isopeptide bond, Phosphoprotein, Ubl conjugation. [Uniprot]
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