anti-UBR7 antibody
CAT.NO. : ARG44983
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概述
产品描述 | Mouse Monoclonal antibody recognizes UBR7 |
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反应物种 | Hu |
应用 | IHC-P, IP, WB |
宿主 | Mouse |
克隆 | Monoclonal |
同位型 | IgG2a |
靶点名称 | UBR7 |
抗原物种 | Human |
抗原表位 | YPDPEDEIPD EMIQCVVCED WFHGRHLGAI PPESGDFQEM VCQACMKRCS FLWAYAAQLA VTKISTEDDG LVRNIDGIGD QEVIKPENGE HQDSTLKEDV PEQGKDDVRE VKVEQNSEPC AGSSSESDLQ TVFKNESLNA ESKSGCKLQE LKAKQLIKKD TATYWPLNWR SKLCTCQDCM KMYGDLDVLF LTDEYDTVLA YENKGKIAQA TDRSDPLMDT LSSMNRVQQV ELICEYNDLK TELKDYLKRF ADEGTVVKRE DIQQFFEEFQ SKKRRRVDGM |
偶联标记 | Un-conjugated |
別名 | UBR7; Ubiquitin Protein Ligase E3 Component N-Recognin7; C14orf130; Ubiquitin Protein Ligase E3 Component N-Recognin7 (Putative); Putative E3 Ubiquitin-Protein Ligase UBR7; RING-Type E3 Ubiquitin Transferase UBR7; N-Recognin-7; Chromosome14 Open Reading Frame130; EC2.3.2.27; LICAS |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Protein A purification |
缓冲液 | PBS with0.09% sodium azide |
抗菌剂 | 0.09% sodium azide |
存放说明 | For continuous use, store undiluted antibody at2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q8N806 Human Putative E3 ubiquitin-protein ligase UBR7 |
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基因名称 | UBR7 |
全名 | Ubiquitin Protein Ligase E3 Component N-Recognin7 |
背景介绍 | This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome. [provided by RefSeq, Jul2016] |
生物功能 | E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. [Uniprot] |
翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation. [Uniprot] |
