anti-UGDH antibody [2G11]
![anti-UGDH antibody [2G11]](/upload/image/products/ARG57074_WB_1_210_205.jpg)
![anti-UGDH antibody [2G11]](/upload/image/products/ARG57074_WB_1.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
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- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG57074
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [2G11] recognizes UGDH |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 2G11 |
| 同位型 | IgG2b, kappa |
| 靶点名称 | UGDH |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-494 of Human UGDH. |
| 偶联标记 | Un-conjugated |
| 別名 | EC 1.1.1.22; UDP-GlcDH; UDP-glucose 6-dehydrogenase; UDP-Glc dehydrogenase; UGD; UDPGDH; GDH |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | UGDH |
| 全名 | UDP-glucose 6-dehydrogenase |
| 背景介绍 | The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
| 生物功能 | Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. [UniProt] |
| 预测分子量 | 55 kDa |
检测图片 (1)
ARG57074 anti-UGDH antibody [2G11] WB image
Western blot: 40 µg of 1) HeLa cell lysate, 2) NIH-3T3 cell lysate, 3) HepG2 cell lysate, 4) A549 cell lysate, 5) MCF7 cell lysate stained with ARG57074 anti-UGDH antibody [2G11] at 1:1000.
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