anti-USP6 / TRE2 / TRE17 antibody
CAT.NO. : ARG63328
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概述
产品描述 | Goat Polyclonal antibody recognizes USP6 / TRE2 / TRE17 |
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反应物种 | Hu |
应用 | WB |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | USP6 / TRE2 / TRE17 |
抗原物种 | Human |
抗原 | KISPLHHLQMECSP |
偶联标记 | Un-conjugated |
別名 | USP6-short; Ubiquitin-specific-processing protease 6; TRE17; TRESMCR; Ubiquitin carboxyl-terminal hydrolase 6; Proto-oncogene TRE-2; Deubiquitinating enzyme 6; Ubiquitin thioesterase 6; Tre-2; TRE2; EC 3.4.19.12; HRP1 |
应用说明
应用建议 |
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应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P35125 Human Ubiquitin carboxyl-terminal hydrolase 6 |
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基因名称 | USP6 |
全名 | ubiquitin specific peptidase 6 |
生物功能 | Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation. [UniProt] |
研究领域 | Cell Biology and Cellular Response antibody; Gene Regulation antibody |
预测分子量 | 159 kDa |
翻译后修饰 | Monubiquitinated; ubiquitination is calmodulin and calcium dependent. |
