anti-VAMP4 antibody
CAT.NO. : ARG41017
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概述
产品描述 | Rabbit Polyclonal antibody recognizes VAMP4 |
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反应物种 | Hu, Ms, Rat |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | VAMP4 |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 1-115 of Human VAMP4 (NP_003753.2). |
偶联标记 | Un-conjugated |
別名 | VAMP24; VAMP-4; Vesicle-associated membrane protein 4 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | Mouse brain | ||||
实际分子量 | 16 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # O70480 Mouse Vesicle-associated membrane protein 4 Swiss-port # O75379 Human Vesicle-associated membrane protein 4 |
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基因名称 | VAMP4 |
全名 | vesicle-associated membrane protein 4 |
背景介绍 | Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport. [provided by RefSeq, Jul 2008] |
生物功能 | Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule. [UniProt] |
细胞定位 | Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Note=Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles. [UniProt] |
预测分子量 | 16 kDa |
