anti-VANGL2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes VANGL2
  • 反应物种: Hu, Ms
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: VANGL2
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human VANGL2 (NP_065068.1)
  • Brand:
CAT.NO. : ARG55511
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes VANGL2
反应物种Hu, Ms
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称VANGL2
抗原物种Human
抗原Recombinant protein of Human VANGL2 (NP_065068.1)
偶联标记Un-conjugated
別名Strabismus 1; STBM; LTAP; Vang-like protein 2; Loop-tail protein 1 homolog; LPP1; STBM1; Van Gogh-like protein 2; STB1
应用说明
预测反应性说明Mouse, Rat
应用建议
应用推荐稀释比
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 57216 Human VANGL2

GeneID: 93840 Mouse VANGL2

Swiss-port # Q91ZD4 Mouse Vang-like protein 2

Swiss-port # Q9ULK5 Human Vang-like protein 2

基因名称VANGL2
全名VANGL planar cell polarity protein 2
背景介绍The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate. [provided by RefSeq, Sep 2011]
生物功能Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity). [UniProt]
研究领域Cell Biology and Cellular Response antibody; Developmental Biology antibody; Neuroscience antibody; Signaling Transduction antibody
预测分子量60 kDa
检测图片 (1)
  • ARG55511 anti-VANGL2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human kidney cancer tissue stained with ARG55511 anti-VANGL2 antibody at 1:100 dilution.

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