anti-VANGL2 antibody
CAT.NO. : ARG55511
US$ Please choose
US$ Please choose
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概述
产品描述 | Rabbit Polyclonal antibody recognizes VANGL2 |
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反应物种 | Hu, Ms |
应用 | IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | VANGL2 |
抗原物种 | Human |
抗原 | Recombinant protein of Human VANGL2 (NP_065068.1) |
偶联标记 | Un-conjugated |
別名 | Strabismus 1; STBM; LTAP; Vang-like protein 2; Loop-tail protein 1 homolog; LPP1; STBM1; Van Gogh-like protein 2; STB1 |
应用说明
预测反应性说明 | Mouse, Rat | ||||||
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应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | VANGL2 |
全名 | VANGL planar cell polarity protein 2 |
背景介绍 | The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate. [provided by RefSeq, Sep 2011] |
生物功能 | Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity). [UniProt] |
研究领域 | Cell Biology and Cellular Response antibody; Developmental Biology antibody; Neuroscience antibody; Signaling Transduction antibody |
预测分子量 | 60 kDa |
