anti-VAPB antibody
CAT.NO. : ARG55008
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概述
产品描述 | Rabbit Polyclonal antibody recognizes VAPB |
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反应物种 | Hu, Rat |
预测物种 | Bov, Pig |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | VAPB |
抗原物种 | Human |
抗原 | KLH-conjugated synthetic peptide corresponding to aa. 126-139 (Center) of Human VAPB. |
偶联标记 | Un-conjugated |
別名 | Vesicle-associated membrane protein-associated protein B/C; ALS8; VAMP-B/VAMP-C; VAMP-associated protein B/C; VAMP-B; VAP-B; VAP-B/VAP-C |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | HeLa |
属性
形式 | Liquid |
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纯化 | Purification with Protein A and immunogen peptide. |
缓冲液 | PBS and 0.09% (W/V) Sodium azide |
抗菌剂 | 0.09% (W/V) Sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # O95292 Human Vesicle-associated membrane protein-associated protein B/C Swiss-port # Q9Z269 Rat Vesicle-associated membrane protein-associated protein B |
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基因名称 | VAPB |
全名 | VAMP (vesicle-associated membrane protein)-associated protein B and C |
背景介绍 | The protein encoded by this gene is a type IV membrane protein found in plasma and intracellular vesicle membranes. The encoded protein is found as a homodimer and as a heterodimer with VAPA. This protein also can interact with VAMP1 and VAMP2 and may be involved in vesicle trafficking. [provided by RefSeq, Jul 2008] |
生物功能 | Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation. [UniProt] |
细胞定位 | Endoplasmic reticulum membrane; Single-pass type IV membrane protein Note=Present in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane. |
研究领域 | Cancer antibody; Metabolism antibody; Signaling Transduction antibody |
预测分子量 | 27 kDa |
