anti-VDAC1 / Porin antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes VDAC1
  • 反应物种: Hu, Ms, Rat
  • 应用: ELISA, FACS, ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: VDAC1
  • 抗原物种: Human
  • 抗原: Human VDAC1 recombinant protein
  • Brand:
CAT.NO. : ARG44010
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes VDAC1
反应物种Hu, Ms, Rat
应用ELISA, FACS, ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称VDAC1
抗原物种Human
抗原Human VDAC1 recombinant protein
表达系统E.coli
偶联标记Un-conjugated
Protein Full nameVoltage-dependent anion-selective channel protein 1
別名VDAC1; Voltage Dependent Anion Channel 1; PORIN; Voltage-Dependent Anion-Selective Channel Protein 1; Outer Mitochondrial Membrane Protein Porin 1; Plasmalemmal Porin; Porin 31HL; Porin 31HM; MGC111064; VDAC-1; Sperm Binding Protein 1a; HVDAC1; VDAC
应用说明
应用建议
应用推荐稀释比
ELISA0.1-0.5 µg/ml
FACS1-3 µg/1x10^6
ICC/IF5 µg/ml
IHC-P2-5 µg/ml
WB0.1-0.25 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose.
稳定剂4% Trehalose
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
生物信息
数据库连接

GeneID: 22333 Mouse VDAC1

GeneID: 7416 Human VDAC1

GeneID: 83529 Rat VDAC1

基因名称VDAC1
全名voltage-dependent anion channel 1
背景介绍This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.[provided by RefSeq, Sep 2010]
生物功能Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. [UniProt]
细胞定位Cell membrane, Membrane, Mitochondrion, Mitochondrion outer membrane. [UniProt]
研究领域Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody
预测分子量31 kDa
翻译后修饰Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation. [UniProt]
检测图片 (6)
  • ARG44010 anti-VDAC1 / Porin antibody IHC-P image

    Immunohistochemistry: Human colorectal adenocarcinoma stained with ARG44010 anti-VDAC1 / Porin antibody at 2 μg/ml dilution.

  • ARG44010 anti-VDAC1 / Porin antibody WB image

    Western blot: A431 and 293T stained with ARG44010anti-VDAC1 / Porin antibody at 0.5 μg/mL dilution.

  • ARG44010 anti-VDAC1 / Porin antibody ICC/IF image

    Immunofluorescence: HELA cells stained with ARG44010 anti-VDAC1 / Porin antibody at 5 μg/ml dilution.

  • ARG44010 anti-VDAC1 / Porin antibody IHC-P image

    Immunohistochemistry: Human liver cancer stained with ARG44010 anti-VDAC1 / Porin antibody at 2 μg/ml dilution.

  • ARG44010 anti-VDAC1 / Porin antibody WB image

    Western blot: Rat heart and Rat liver stained with ARG44010 anti-VDAC1 / Porin antibody at 0.5 μg/mL dilution.

  • ARG44010 anti-VDAC1 / Porin antibody WB image

    Western blot: Mouse heart and Mouse liver stained with ARG44010 anti-VDAC1 / Porin antibody at 0.5 μg/mL dilution.

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