anti-WASF2 / WAVE2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG44291
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes WASF2 / WAVE2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | WASF2 / WAVE2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide |
| 偶联标记 | Un-conjugated |
| 別名 | WASF2; WASP Family Member 2; WAVE2; SCAR2; Wiskott-Aldrich Syndrome Protein Family Member 2; Verprolin Homology Domain-Containing Protein 2; WASP Family Protein Member 2; WAS Protein Family Member 2; Actin-Binding Protein WASF2; Protein WAVE-2 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | ~ 85 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified |
| 缓冲液 | PBS with 1 mg/ml BSA, 0.05% Sodium azide and 50% glycerol |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 1 mg/ml BSA and 50% glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
| 数据库连接 | Swiss-port # Q8BH43 Mouse Wiskott-Aldrich syndrome protein family member 2 Swiss-port # Q9Y6W5 Human Wiskott-Aldrich syndrome protein family member 2 |
|---|---|
| 基因名称 | WASF2 |
| 全名 | WASP Family Member 2 |
| 背景介绍 | This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene. |
| 生物功能 | Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. |
| 细胞定位 | Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane |
| 预测分子量 | 52 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (1)
ARG44291 anti-WASF2 / WAVE2 antibody WB image
Western blot: PC12 stained with ARG44291 anti-WASF2 / WAVE2 antibody.
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