anti-WDR45 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG23721
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes WDR45 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | WDR45 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around aa. 312-322 of Human WDR45. |
| 偶联标记 | Un-conjugated |
| 別名 | WD repeat-containing protein 45; WIPI-4; NBIA5; NBIA4; WIPI4; JM5; WD repeat domain phosphoinositide-interacting protein 4; WDRX1 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | ~ 40 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.09% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q9Y484 Human WD repeat domain phosphoinositide-interacting protein 4 |
|---|---|
| 基因名称 | WDR45 |
| 全名 | WD repeat domain 45 |
| 背景介绍 | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays an important role in the autophagy pathway, which is the major intracellular degradation system by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. [UniProt] |
| 预测分子量 | 40 kDa |
检测图片 (2)
ARG23721 anti-WDR45 antibody ICC/IF image
Immunofluorescence: HeLa cells fixed with 4% Formaldehyde for 15 min at RT. Cells were stained with ARG23721 anti-WDR45 antibody at 1:100 for 60 min at RT. Magnification: 60X. (A) DAPI. (B) Phalloidin Texas Red F-Actin stain. (C) Primary antibodies. (D) Composite.
ARG23721 anti-WDR45 antibody WB image
Western blot: 15 µg of Human 293Trap cell lysates stained with ARG23721 anti-WDR45 antibody at 1:1000 for 1 hour at RT.
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