anti-Wnt2b antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG59219
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Wnt2b |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 预测物种 | Hm |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Wnt2b |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 87-112 of Human Wnt2b. (QRYPDIMRSVGEGAREWIRECQHQFR) |
| 偶联标记 | Un-conjugated |
| 別名 | Protein Wnt-13; WNT13; Protein Wnt-2b |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: By heat mediation. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | WNT2B |
| 全名 | wingless-type MMTV integration site family, member 2B |
| 背景介绍 | This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
| 生物功能 | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis. [UniProt] |
| 细胞定位 | Secreted, extracellular space, extracellular matrix. Secreted. [UniProt] |
| 预测分子量 | 44 kDa |
| 翻译后修饰 | Palmitoleylation is required for efficient binding to frizzled receptors. Depalmitoleylation leads to Wnt signaling pathway inhibition. [UniProt] |
检测图片 (4)
ARG59219 anti-Wnt2b antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain stained with ARG59219 anti-Wnt2b antibody.
ARG59219 anti-Wnt2b antibody WB image
Western blot: 40 µg of 22RV1 whole cell lysate stained with ARG59219 anti-Wnt2b antibody at 0.5 µg/ml dilution.
ARG59219 anti-Wnt2b antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat brain stained with ARG59219 anti-Wnt2b antibody.
ARG59219 anti-Wnt2b antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human lung cancer stained with ARG59219 anti-Wnt2b antibody.
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