anti-Wnt5b antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Wnt5b
  • 反应物种: Hu, Ms, Rat
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Wnt5b
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human WNT5B
  • Brand:
CAT.NO. : ARG56400
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Wnt5b
反应物种Hu, Ms, Rat
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Wnt5b
抗原物种Human
抗原Recombinant protein of Human WNT5B
偶联标记Un-conjugated
別名Protein Wnt-5b
应用说明
应用建议
应用推荐稀释比
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照SH-SY5Y
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 22419 Mouse WNT5B

GeneID: 81029 Human WNT5B

Swiss-port # P22726 Mouse Protein Wnt-5b

Swiss-port # Q9H1J7 Human Protein Wnt-5b

基因名称WNT5B
全名wingless-type MMTV integration site family, member 5B
背景介绍The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
生物功能Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). [UniProt]
预测分子量40 kDa
翻译后修饰Palmitoleylation is required for efficient binding to frizzled receptors. Depalmitoleylation leads to Wnt signaling pathway inhibition.
检测图片 (2)
  • ARG56400 anti-Wnt5b antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse lung stained with ARG56400 anti-Wnt5b antibody at 1:100 dilution.

  • ARG56400 anti-Wnt5b antibody WB image

    Western blot: SH-SY5Y cell lysate stained with ARG56400 anti-Wnt5b antibody.

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