anti-Wnt7a antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG41733
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Wnt7a |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 预测物种 | Bov |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Wnt7a |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 226-256 of Human Wnt7a. (YVLKDKYNEAVHVEPVRASRNKRPTFLKIKK) |
| 偶联标记 | Un-conjugated |
| 別名 | Protein Wnt-7a |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | ~ 39 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | WNT7A |
| 全名 | wingless-type MMTV integration site family, member 7A |
| 背景介绍 | This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes. [provided by RefSeq, Jul 2008] |
| 生物功能 | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts (By similarity). [UniProt] |
| 细胞定位 | Secreted, extracellular space, extracellular matrix. Secreted. [UniProt] |
| 预测分子量 | 39 kDa |
| 翻译后修饰 | Palmitoleylation is required for efficient binding to frizzled receptors. Depalmitoleylation leads to Wnt signaling pathway inhibition. [UniProt] |
检测图片 (2)
ARG41733 anti-Wnt7a antibody WB image
Western blot: Rat kidney, Rat liver ,Mouse kidney stained with ARG41733 anti-Wnt7a antibody at 1:1000 dilution.
ARG41733 anti-Wnt7a antibody FACS image
Flow Cytometry: PC-3 cells stained with ARG10766 anti-ABCB4 / MDR3 antibody ARG41733 anti-Wnt7a antibody at 1:500 dilution / 1x10^6 cells.
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