anti-XPB antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes XPB
  • 反应物种: Hu, Ms, Rat
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: XPB
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 512-782 of Human XPB (NP_000113.1).
  • Brand:
CAT.NO. : ARG59617
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes XPB
反应物种Hu, Ms, Rat
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称XPB
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 512-782 of Human XPB (NP_000113.1).
偶联标记Un-conjugated
別名TFIIH 89 kDa subunit; TFIIH basal transcription factor complex helicase XPB subunit; TTD2; RAD25; TFIIH p89; TFIIH basal transcription factor complex 89 kDa subunit; BTF2; Basic transcription factor 2 89 kDa subunit; XPB; BTF2 p89; DNA repair protein complementing XP-B cells; Xeroderma pigmentosum group B-complementing protein; EC 3.6.4.12; TFIIH; GTF2H; DNA excision repair protein ERCC-3
应用说明
应用建议
应用推荐稀释比
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Rat kidney, Mouse kidney and Jurkat
实际分子量89 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 13872 Mouse ERCC3

GeneID: 2071 Human ERCC3

GeneID: 291703 Rat ERCC3

基因名称ERCC3
全名excision repair cross-complementation group 3
背景介绍This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
生物功能ATP-dependent 3'-5' DNA helicase, component of the core-TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage. [UniProt]
细胞定位Nucleus. [UniProt]
预测分子量89 kDa
检测图片 (1)
  • ARG59617 anti-XPB antibody WB image

    Western blot: 25 µg of Rat kidney, Mouse kidney and Jurkat cell lysates stained with ARG59617 anti-XPB antibody at 1:3000 dilution.

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