anti-ZFYVE19 / ANCHR antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG65803
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ZFYVE19 / ANCHR |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ZFYVE19 / ANCHR |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide around the center region of Human ZFYVE19 / ANCHR. |
| 偶联标记 | Un-conjugated |
| 別名 | MPFYVE; Zinc finger FYVE domain-containing protein 19; ANCHR; Abscission/NoCut checkpoint regulator; MLL partner containing FYVE domain |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 0.2% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.2% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q96K21 Human Abscission/NoCut checkpoint regulator |
|---|---|
| 基因名称 | ZFYVE19 |
| 全名 | zinc finger, FYVE domain containing 19 |
| 生物功能 | Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission. [UniProt] |
| 预测分子量 | 52 kDa |
检测图片 (2)
ARG65803 anti-ZFYVE19 / ANCHR antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human breast cancer tissue section. Antigen retrieval: Heat mediated with Sodium citrate buffer (pH 6.0). The section was then stained with ARG65803 anti-ZFYVE19 / ANCHR antibody at RT and detected using an HRP conjugacompact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
ARG65803 anti-ZFYVE19 / ANCHR antibody WB image
Western blot: Raji, A431 and HT29 whole cell lysates stained with ARG65803 anti-ZFYVE19 / ANCHR antibody.
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