anti-ZYX antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes ZYX
  • 反应物种: Hu
  • 预测物种: Dog
  • 应用: WB
  • 特异性: Reported variants represent identical protein: NP_003452.1, NP_001010972.1
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: ZYX
  • Brand:
CAT.NO. : ARG65106
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes ZYX
反应物种Hu
预测物种Dog
应用WB
特异性Reported variants represent identical protein: NP_003452.1, NP_001010972.1
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称ZYX
抗原物种Human
抗原C-QQREKPRVQEKQH
偶联标记Un-conjugated
別名Zyxin; HED-2; ESP-2; Zyxin-2
应用说明
应用建议
应用推荐稀释比
WB0.1 - 0.3 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 7791 Human ZYX

Swiss-port # Q15942 Human Zyxin

背景介绍Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008]
研究领域Gene Regulation antibody; Neuroscience antibody; Signaling Transduction antibody
预测分子量61 kDa
检测图片 (1)
  • ARG65106 anti-ZYX antibody WB image

    Western Blot: Peripheral Blood Mononucleocytes lysate (35 µg protein in RIPA buffer) stained with ARG65106 anti-ZYX antibody at 0.1 µg/ml dilution.

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