B7-H3 Rabbit Monoclonal Antibody(ARM598)
Key features and details
- Target:
- Clone ID:
- Host:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6889
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Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
B7 homolog 3 (B7-H3), also known as CD276, belongs the B7 immunoglobulin superfamily of cell surface ligands that regulate T cell activation and immune responses. Soluble B7-H3 binds a putative receptor on activated T-cells that is distinct from CD28, CTLA-4, ICOS and PD-1. B7-H3 is expressed by antigen presenting cells, activated T cells, and a few normal tissues, including placenta and prostate. Expression of B7-H3 is also seen in several cancer types, such as prostate, breast, colon, lung, and gastric cancers.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:50 - 1:200 |
Overview
|
Molecular Weight |
57,235 Da |
|
Chromosome Location |
Chromosome: 15; NC_000015.9 (73976622..74006859). Location: 15q23-q24 |
|
3D Structure |
ModBase 3D Structure for Q5ZPR3 |
|
Isotype |
IgG |
|
Host |
Rabbit |
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Species Reactivity |
Human |
|
Purity/Purification |
Purified |
|
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
|
Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human tonsil tissue using B7-H3 Rabbit Monoclonal Antibody (ARM598).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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