Beta Amyloid 1-40 Mouse Monoclonal Antibody (ARA991)
Key features and details
- Reactivity:Human
- Application:Sandwich ELISA
- Host:Mouse
- Clonality:Monoclonal
- Target:Beta Amyloid 1-40
-
Brand:
CAT.NO. : ARA6889
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Product Details
Background
β-Amyloid (1-40), Iowa mutation is a biologically active peptide. (Several mutations in the beta amyloid precursor gene lead to autosomal dominant Alzheimer's disease in many families. Iowa mutations (where Asp 23 is replaced by Asn) are associated with severe brain amyloid vascular disease (CAA). The affected individuals have a missense mutation at APP 694. The mutated beta-amyloid peptides accumulate faster and form toxic fibrils
Application
| Recommended dilution ratio | |
|---|---|
| Sandwich ELISA | 1:250~1:500 |
Formulation
| ARA6889 | Phosphate-buffered saline (PBS), carrier-free, with optional 0.09% sodium azide |
|---|---|
| ARA6889-T5/20/50/100 | Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide |
Overview
|
Antibody specificity |
Recognizing beta Amyloid 1-40 with an epitope within 15 amino acids at the C-terminus of beta Amyloid 1-40 |
|
Species reactivity |
Human |
|
Clonality |
Monoclonal |
|
Host / isotype |
Mouse / IgG2b |
|
Immunogen |
Human amyloid beta precursor peptide |
|
Cross reactivity |
Not tested |
|
Recombinant |
Not recombinant |
|
Purification |
Protein A purification |
|
Form |
Liquid |
|
Conjugation |
Unconjugated |
Data
Sandwich ELISA analysis of Beta Amyloid 1-40 by ARA6889 & mouse anti-Beta Amyloid 1-40 monoclonal antibody .
Microtiter wells were coated with ARA6889 as the capture antibody. Synthetic peptide corresponding to amino acids 1-40 of human beta amyloid was used as the antigen. Peroxidase conjugated mouse anti-Beta Amyloid 1-40 monoclonal antibody was used as the detection antibody.
Result: ARA6889 and mouse anti-Beta Amyloid 1-40 monoclonal antibody can be used as a matched antibody pair to detect and quantify the concentration of Beta Amyloid 1-40.
Storage
Shipped at ambient temperature or with ice packs. Avoid repeated freeze-thaw cycles.
Upon receipt,
* 1 month when stored at 2 to 8 °C
* 12 months when aliquoted and stored at -20 °C or below
Upon receipt,
* 1 month when stored at 2 to 8 °C
* 12 months when aliquoted and stored at -20 °C or below
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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