Broad-Reactive Avian Influenza NP Mouse Monoclonal Antibody (ANP_4B5)
Key features and details
- Product:
- Clone:
- Host:
- Species Reactivity:
- Application:
- Immunogen :
- Clone Type:
- Storage:
-
Brand:
CAT.NO. : AXA0013
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Product Details
Background
Avian influenza virus NP is a highly conserved structural protein, serving as a core component of the viral ribonucleoprotein complex. It is responsible for encapsidating the viral genomic RNA, protecting it from host nuclease degradation, and mediating key processes in viral replication and assembly. Due to its low sequence variability across diverse avian influenza subtypes (including H1, H3, H6, H9, H10, H12, etc.), NP becomes an ideal target for developing broad-spectrum research tools and intervention strategies. Broad-reactive agents targeting avian influenza NP can bind to conserved epitopes of NP, enabling cross-subtype detection, neutralization, or immune activation. This property is crucial for addressing the challenges posed by the constant emergence of new avian influenza subtypes and viral antigenic drift, supporting the development of universal diagnostic reagents, vaccines, and antiviral therapies for avian influenza control.
Application
|
Application |
Recommended Dilution Ratio/Concentration |
|
WB |
1:1000-2000 |
Overview
| Host | Mouse |
| Clonality | Monoclonal |
| Applications | WB, IFA, ELISA |
| Reactivity | Reacts with multiple influenza A subtypes (H3, H6, H9, H10, H12) |
| Appearance | Liquid |
| Storage Buffer | PBS, 20% Glycerol; Preservative: 0.05% Sodium Azide |
| Storage Conditions | Store at -20°C, valid for 1 year. Avoid repeated freeze-thaw cycles. |
| Concentration | 1.45 mg/ml |
| Immunogen | Avian Influenza H10 |
Data
Figure 1-1 WB Characterization of FluA-NP Monoclonal Antibody
1: MDCK cells infected with H9 AIV 2: MDCK cells Figure 1-2 IFA
Reaction of Monoclonal Antibody with Different Influenza Virus Subtypes
WB and IFA results demonstrate that this antibody effectively recognizes the NP protein expressed in 293T cells transfected with the eukaryotic expression plasmid pC-NP, as well as H9 AIV-infected MDCK cells.
1: MDCK cells infected with H9 AIV 2: MDCK cells Figure 1-2 IFA
Reaction of Monoclonal Antibody with Different Influenza Virus Subtypes
WB and IFA results demonstrate that this antibody effectively recognizes the NP protein expressed in 293T cells transfected with the eukaryotic expression plasmid pC-NP, as well as H9 AIV-infected MDCK cells.
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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