Broad-Reactive Influenza A NP Mouse Monoclonal Antibody (ANP_2G2)
CAT.NO. : AXA0012
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Background
Broad-Reactive Influenza A NP refers to a molecular entity that exhibits cross-reactivity with the nucleoprotein (NP) of multiple influenza A virus subtypes. Influenza A virus NP is a highly conserved structural protein that plays crucial roles in viral replication and assembly. It encapsidates the viral genomic RNA to form ribonucleoprotein complexes, protecting the genome from host nuclease degradation and mediating intracellular transport of viral components. Due to its low mutation rate across different influenza A subtypes (including H1N1, H3N2, H5N1, H7N9, etc.), NP becomes an ideal target for developing broad-spectrum diagnostic tools, universal vaccines, and antiviral therapies. Broad-reactive agents targeting influenza A NP can recognize conserved epitopes of NP, enabling cross-subtype detection or neutralization of influenza A viruses, which helps address the challenges posed by viral antigenic drift and the emergence of novel subtypes.
Application
|
Application |
Recommended Dilution Ratio/Concentration |
|
IFA |
0.597222 |
|
IP |
3mg |
|
WB |
1:1000-2000 |
Overview
| Host | Mouse |
| Clonality | Monoclonal |
| Applications | WB, IFA, ELISA |
| Reactivity | Reacts with multiple influenza A subtypes (H3, H6, H9, H10, H12) |
| Appearance | Liquid |
| Storage Buffer | PBS, 20% Glycerol; Preservative: 0.05% Sodium Azide |
| Storage Conditions | Store at -20°C, valid for 1 year. Avoid repeated freeze-thaw cycles. |
| Concentration | 1.45 mg/ml |
| Immunogen | Avian Influenza H10 |
Data
Figure 1-1 WB Characterization of FluA-NP Monoclonal Antibody


WB and IFA results demonstrate that this antibody effectively recognizes the NP protein expressed in 293T cells transfected with the eukaryotic expression plasmid pC-NP, as well as H9 AIV-infected MDCK cells.


WB and IFA results demonstrate that this antibody effectively recognizes the NP protein expressed in 293T cells transfected with the eukaryotic expression plasmid pC-NP, as well as H9 AIV-infected MDCK cells.
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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