Broad-Reactive Influenza B NP Mouse Monoclonal Antibody (BNP_1H9)
Key features and details
- Product:
- Clone:
- Host:
- Species Reactivity:
- Application:
- Immunogen :
- Clone Type:
- Storage:
-
Brand:
CAT.NO. : AXA0014
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Influenza B virus, a member of the Orthomyxoviridae family, is a major human respiratory pathogen that circulates globally, causing seasonal influenza outbreaks. Unlike influenza A virus, influenza B virus has no animal reservoirs and is classified into two main lineages: Victoria and Yamagata. The NP of influenza B virus is a highly conserved structural protein, functioning as a core component of the viral ribonucleoprotein complex. It is responsible for encapsidating the viral negative-sense RNA genome, protecting it from host nuclease degradation, and facilitating critical steps in viral replication, transcription, and intracellular transport. Due to its low sequence variability across different influenza B strains and lineages, NP is a key target for developing broad-reactive diagnostic tools, universal vaccines, and antiviral therapies. Broad-reactive agents targeting influenza B NP can bind to conserved epitopes, enabling cross-strain detection and neutralization, which is essential for combating the continuous circulation and evolution of influenza B virus.
Application
|
Application |
Recommended Dilution Ratio |
|
IFA |
1:200-1:500 |
|
WB |
1:500-1:1000 |
*The optimal dilution ratio/concentration should be determined by researchers.
Overview
| Host | Mouse |
| Clonality | Monoclonal |
| Applications | WB, IFA, ELISA |
| Reactivity | Reacts with influenza B virus |
| Appearance | Liquid |
| Storage Buffer | PBS, 20% Glycerol; Preservative: 0.05% Sodium Azide |
| Storage Conditions | Store at -20°C, valid for 1 year. Avoid repeated freeze-thaw cycles. |
| Concentration | 0.54 mg/ml |
| Immunogen | Prokaryotically expressed influenza B NP protein |
Data
Figure 1-1 Western Blot Characterization of FluB-NP Monoclonal Antibody
1：rBac FluB-NP 2：rBac-vector
Figure 1-2 IFA Specificity of FluB-NP Monoclonal Antibody
WB and IFA results demonstrate that it can effectively recognize the NP protein expressed in SF9 cells infected with the baculovirus rBev-NP.
1：rBac FluB-NP 2：rBac-vector
Figure 1-2 IFA Specificity of FluB-NP Monoclonal Antibody
WB and IFA results demonstrate that it can effectively recognize the NP protein expressed in SF9 cells infected with the baculovirus rBev-NP.
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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