c-Myc Rabbit Monoclonal Antibody(ARM968)
CAT.NO. : ARM6758
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Background
c-Myc is a phosphoprotein involved with cell proliferation and differentiation. It is a useful marker for differentiation between Burkitt's lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL) since, despite morphological similarities between the two B-cell lymphomas, Anti-c-Myc stains all BL and only a few DLBCL cases. A panel of antibodies against c-Myc, CD10, BCL2, and Ki-67 is useful for cases where Myc FISH analysis is warranted or can be omitted. Nuclear c-Myc overexpression is common in luminal cells of prostate intraepithelial neoplasia, many primary carcinomas, and metastatic disease.
Application
Application |
Dilution Ratio |
IHC |
1:25 - 1:100 |
Overview
Molecular Weight |
48,804 Da |
Chromosome Location |
Chromosome: 8; NC_000008.10 (128748315..128753680). Location: 8q24.21 |
3D Structure |
ModBase 3D Structure for P01106 |
Isotype |
IgG |
Host |
Rabbit |
Species Reactivity |
Human |
Purity/Purification |
Purified |
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
Immunogen |
Recombinant Protein |
Data

Immunohistochemical staining of human tonsil tissue using c-Myc Rabbit Monoclonal Antibody (ARM968).
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
