c-Myc Rabbit Monoclonal Antibody(ARM968)

Key features and details

  • Target: c-Myc
  • Clone ID: ARM968
  • Host Species: Rabbit
  • Species Cross-reactivity: Human
  • Applications: IHC-P
  • Dilution: 1:25-1:100
  • Clonality: Monoclonal
  • Brand:
CAT.NO. : ARM6758
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Size:
1mL
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Product Details
Background
c-Myc is a phosphoprotein involved with cell proliferation and differentiation. It is a useful marker for differentiation between Burkitt's lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL) since, despite morphological similarities between the two B-cell lymphomas, Anti-c-Myc stains all BL and only a few DLBCL cases. A panel of antibodies against c-Myc, CD10, BCL2, and Ki-67 is useful for cases where Myc FISH analysis is warranted or can be omitted. Nuclear c-Myc overexpression is common in luminal cells of prostate intraepithelial neoplasia, many primary carcinomas, and metastatic disease.
Application

Application

Dilution Ratio

IHC

1:25 - 1:100

Overview

Molecular Weight

48,804 Da

Chromosome Location

Chromosome: 8; NC_000008.10 (128748315..128753680). Location: 8q24.21

3D Structure

ModBase 3D Structure for P01106

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Purity/Purification

Purified

Form/Format

Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide

Immunogen

Recombinant Protein

Data


Immunohistochemical staining of human tonsil tissue using c-Myc Rabbit Monoclonal Antibody (ARM968).
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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