Calcitonin Rabbit Monoclonal Antibody(ARB885)

Key features and details

  • Target: Calcitonin
  • Clone ID: ARB885
  • Host: Rabbit
  • Molecular Weight: 15.5 kDa
  • Purity: ProA affinity purified IgG
  • Species Cross-reactivity: Human
  • Applications: IHC-P
  • Swissprot ID: P01258
  • Brand:
CAT.NO. : ARB6677
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Size:
1mL
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Product Details
Background
Calcitonin (CT) is a 32 amino acid peptide synthesized by the parafollicular C cells of the thyroid. It acts through its receptors to inhibit osteoclast mediated bone resorption, decrease calcium resorption by kidney and decrease calcium absorption by intestines. The action of calcitonin is therefore to cause a reduction in serum calcium, an effect opposite to that of parathyroid hormone.

The antibody is useful for the identification of calcitonin-producing C cells and is a useful aid for classification of medullary thyroid carcinoma.
Overview
Target Calcitonin
Host Species rabbit monoclonal antibody
Molecular Weight 15.5 kDa
Purity ProA affinity purified IgG
Species Cross-reactivity Human
Form Liquid
Applications IHC-P
Swissprot ID P01258
Immunogen Synthetic peptide corresponding to residues in Human Calcitonin
Storage Buffer PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%
Storage Conditions -25°C to -18°C
Dilutions IHC-P: 1:100-1:200
Subcellular Location Cytoplasm
Recommended Method Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes
Data

Immunohistochemical staining of human medullary thyroid carcinoma tissue sections using Calcitonin Rabbit Monoclonal Antibody (ARB885).
Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Research Use Only

For Research Use Only. Not for use in diagnostic procedures.

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