Calretinin Mouse Monoclonal Antibody(ARM601)

Key features and details

  • Target: Calretinin
  • Clone ID: ARM601
  • Host: Mouse
  • Species Cross-reactivity: Human
  • Applications: IHC
  • Dilution: 1:50-1:200
  • Clonality: Monoclonal
  • Brand:
CAT.NO. : ARM6892
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Product Details
Background
Calretinin is a calcium-binding protein that functions as a modulator of neuronal excitability and may play a protective role in the survival of nerve cells during disturbances in calcium homeostasis. It is abundantly expressed in subsets of neurons throughout the brain and spinal cord, particularly retina and sensory ganglia, but it is also found in mesothelium, eccrine sweat glands, Sertoli cells, ovarian stromal cells, and adrenal cortical cells. Due to its high sensitivity against mesothelial cells, calretinin is a useful marker in differentiating mesothelioma and metastatic adenocarcinoma to the serous membranes. It is also a diagnostic marker of Hirschsprung's disease and some ovarian and testicular cancers such as Sertoli-Leydig cell tumour, Sertoli cell tumour, Leydig cell tumour, sex cord tumour with annular tubules, and steroid cell tumour.
Application

Application

Dilution Ratio

IHC

1:25 - 1:100

Overview

Molecular Weight

31,540 Da

3D Structure

ModBase 3D Structure for P22676

Isotype

IgG1

Host

Mouse

Species Reactivity

Human

Purity/Purification

Purified

Form/Format

Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide

Immunogen

Recombinant Protein

Data

Immunohistochemical staining of human appendix tissue using Calretinin Mouse Monoclonal Antibody (ARM601).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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