CD10 Rabbit Monoclonal Antibody(ARM886)

Key features and details

  • Target: CD10
  • Clone ID: ARM886
  • Host Species: Rabbit
  • Species Cross-reactivity: Human
  • Applications: IHC-P
  • Dilution: 1:50-1:200
  • Clonality: Monoclonal
  • Brand:
CAT.NO. : ARM6676
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Size:
1mL
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Cluster of Differentiation 10 (CD10) is a cell surface metalloendopeptidase that cleaves and inactivates several peptide hormones including glucagon, enkephalins, and oxytocin. Also known as Common Acute Lymphoblastic Leukemia Antigen (CALLA), it is an important cell surface marker in the diagnosis of human ALL (Acute Lymphocytic Leukemia), and is found positive in precursor B lymphoblastic leukemia/lymphoma, angioimmunoblastic T-cell lymphoma, Burkitt's lymphoma, and follicular germinal center lymphoma. CD10 expression has also been reported in a variety of non-hematolymphoid tissues, particularly of the kidney. It is a useful aid in the diagnosis of various malignant tumours such as renal cell carcinoma, endometrial stromal sarcoma, and hepatocellular carcinoma.
Application

Application

Dilution Ratio

IHC

1:50 - 1:200

Overview

Molecular Weight

750

Chromosome Location

Chromosome: 3; NC_000003.11 (154797436..154901518). Location: 3q25.2

3D Structure

ModBase 3D Structure for P08473

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Purity/Purification

Purified

Form/Format

Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide

Immunogen

Recombinant Protein

Data

Immunohistochemical staining of human tonsil tissue using CD10 Rabbit Monoclonal Antibody (ARM886).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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