CD14 Rabbit Monoclonal Antibody(ARB890)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
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Brand:
CAT.NO. : ARB6682
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Product Details
Background
CD14 is receptor for endotoxin and apoptotic cells. It is expressed by monocytes/histiocytes, Langerhans' cells, follicular dendritic reticulum cells, neutrophils (weakly), and endothelial cells of the liver sinusoids.
CD14 is detected in myeloid leukaemias with monoblastic/monocytic differentiation, and in histiocytic neoplasms like histiocytic lymphoma, Langerhans' cell histiocytosis and giant cell tumour. In cultures, a subpopulation of Kaposi sarcoma cells express CD14.
In differential diagnosis, CD14 is more specific than CD68 in the identification of monocytes/histiocytes and associated neoplasias.
CD14 is detected in myeloid leukaemias with monoblastic/monocytic differentiation, and in histiocytic neoplasms like histiocytic lymphoma, Langerhans' cell histiocytosis and giant cell tumour. In cultures, a subpopulation of Kaposi sarcoma cells express CD14.
In differential diagnosis, CD14 is more specific than CD68 in the identification of monocytes/histiocytes and associated neoplasias.
Overview
| Target | CD14 |
| Host Species | rabbit monoclonal antibody |
| Molecular Weight | 40 kDa |
| Purity | ProA affinity purified IgG |
| Species Cross-reactivity | Human |
| Form | Liquid |
| Applications | IHC-P |
| Swissprot ID | P08571 |
| Immunogen | Synthetic peptide corresponding to residues within aa1-100 of CD14 |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
| Storage Conditions | -25°C to -18°C |
| Dilutions | IHC-P: 1:100-1:200 |
| Subcellular Location | Membrane |
| Recommended Method | Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes |
data
Immunohistochemical staining of human appendiceal tissue sections using CD14 Rabbit Monoclonal Antibody (ARB890).
Immunohistochemical staining of human lung adenocarcinoma tissue sections using CD14 Rabbit Monoclonal Antibody (ARB890).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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