CD14 Rabbit Monoclonal Antibody(ARM937)
CAT.NO. : ARM6727
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Background
Cluster of Differentiation 14 (CD14) is a macrophage-derived monocyte marker that stains granulocytes, endothelial and epithelial cells, placental trophoblasts, and the red pulp and marginal zone cells of the spleen. In lymph nodes, sinusoidal histiocytes and follicular dendritic cells stain positively for CD14, while monocyte-derived cells, including macrophages associated with anthracosis and sinusoidal histiocytosis with erythrophagocytosis, stain negatively. High CD14 expression is found in histiocytes with Diffuse Large B-Cell Lymphoma (DLBCL) when compared to Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL), Mantle Cell Lymphoma (MCL), or Follicular Lymphoma (FL). CD14 is also valuable for differentiating between acute monocytic leukemia, myeloproliferative neoplasms, and myelodysplastic syndrome.
Application
Application |
Dilution Ratio |
IHC |
1:50 - 1:200 |
Overview
Molecular Weight |
40,076 Da |
3D Structure |
ModBase 3D Structure for P08571 |
Isotype |
IgG |
Host |
Rabbit |
Species Reactivity |
Human |
Purity/Purification |
Purified |
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
Immunogen |
Recombinant Protein |
Data

Immunohistochemical staining of human lymph node tissue using CD14 Rabbit Monoclonal Antibody (ARM937).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
