CD20 Rabbit Monoclonal Antibody(ARA740)
Key features and details
- Target:
- Clone ID:
- Host:
- Clone Type:
- Purity:
- Species Cross-reactivity:
- Applications:
- Isotype:
-
Brand:
CAT.NO. : ARA6527
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
Product Details
Background
CD20 is a leukocyte surface antigen consisting of four transmembrane regions and cytoplasmic N and C-termini. CD20 is expressed primarily on B cells but has also been detected on both normal and neoplastic T cells. CD20 functions as a calcium-permeable cation channel, and it is known to accelerate the G0 to G1 progression induced by IGF-1. CD20 is activated by the IGF-1 receptor via the α subunits of the heterotrimeric G proteins. Activation of CD20 significantly increases DNA synthesis and is thought to involve basic helix-loop-helix leucine zipper transcription.
Application
|
Application |
Dilution Ratio |
|
IHC-P |
1:2,000-1:5,000 |
|
IF/ICC |
1:100-1:500 |
|
FC |
1:10-1:20 |
|
IP |
1:1,000-1:2,000 |
|
WB |
1:400-1:1,000 |
Overview
|
Host Species |
Rabbit |
|
Species Cross-reactivity |
Human |
|
Application |
IHC-P, IF/ICC, FC, IP, WB |
|
Immunogen |
A synthetic peptide corresponding to residues on the C-terminus of human CD20 was used as an immunogen. |
|
Purity |
ProA affinity purified IgG |
|
Clone Type |
Recombinant Monoclonal |
|
Isotype |
IgG |
|
Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA |
Storage
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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