CD25 Rabbit Monoclonal Antibody(ARM945)
Key features and details
- Target:
- Clone ID:
- Host Species:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6735
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Cluster of Differentiation 25 (CD25) is the extracellular region of the interleukin-2 receptor on activated B- and T-cells, myeloid precursors, and some other types of leukocytes. Since CD25 staining is useful for differentiating neoplastic mast cell aggregates from reactive proliferations, Anti-CD25 has become a major criterion for Systemic Mastocytosis diagnoses. In the context of urticaria pigmentosa, CD25 staining is also used to recognize mast cells in skin biopsies. There is a greater proportion of CD25+ and FOXP3+ regulatory T-cells among cancer cells in tumour parenchyma and its periphery in recurrent cutaneous melanoma compared to non-recurrent melanoma.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:50 - 1:200 |
Overview
|
Molecular Weight |
30,819 Da |
|
Chromosome Location |
Chromosome: 10; NC_000010.10 (6052657..6104333, complement). Location: 10p15-p14 |
|
3D Structure |
ModBase 3D Structure for P01589 |
|
Isotype |
IgG |
|
Host |
Rabbit |
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Species Reactivity |
Human |
|
Purity/Purification |
Purified |
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Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
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Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human spleen tissue using CD25 Rabbit Monoclonal Antibody (ARM945).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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