CD30 Rabbit Monoclonal Antibody(ARA743)
Key features and details
- Target:
- Clone ID:
- Host:
- Clone Type:
- Purity:
- Species Cross-reactivity:
- Applications:
- Isotype:
-
Brand:
CAT.NO. : ARA6530
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
Product Details
Background
CD30, TNF-receptor superfamily member, is a receptor for TNFSF8/CD30L. TRAF2 and TRAF5 can interact with this receptor and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and it also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.CD30 is expressed in mononuclear Hodgkin’s and multinucleated Reed-Sternberg cells in Hodgkin’s disease, in tumor cells of a majority of anaplastic large cell lymphomas, in a varying proportion of activated T and B cells. In non-lymphoid malignancies, CD30 reactivity has been reported in embryonal carcinomas (ECs), seminomas, and hepatocellular carcinomas.This antibody has been useful in identifying Hodgkin's lymphoma, anaplastic large cell lymphomas (ALCL) and primary cutaneous CD30+ T-cell lymphoproliferative disorders.
Application
|
Application |
Dilution Ratio |
|
IHC-P |
1:2,000-1:5,000 |
|
IF/ICC |
1:100-1:500 |
|
FC |
1:10-1:20 |
|
IP |
1:1,000-1:2,000 |
|
WB |
1:400-1:1,000 |
Overview
|
Host Species |
Rabbit |
|
Species Cross-reactivity |
Human |
|
Application |
IHC-P, IF/ICC, FC, IP, WB |
|
Immunogen |
A synthetic peptide corresponding to residues on the C-terminus of human CD20 was used as an immunogen. |
|
Purity |
ProA affinity purified IgG |
|
Clone Type |
Recombinant Monoclonal |
|
Isotype |
IgG |
|
Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA |
Storage
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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