CD318 Mouse Monoclonal Antibody(ARA933)
Key features and details
- Reactivity:Human, Mouse, Rat
- Application:WB
- Host:Mouse
- Clonality:Monoclonal
- Target:CD318
-
Brand:
CAT.NO. : ARA6771
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Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
CD318/CDCP1 (CUB-domain-containing protein 1) contains three extracellular CUB domains, a transmembrane domain, and two putative cytoplasmic tyrosine phosphorylation sites. Phosphorylation of the gp140 and p80 proteins is mediated by Src family kinases at various tyrosine residues, including Tyr 734. PTP family members mediate the desphosphorylation of CDCP1. The conversion of gp140 to p80 prolongs the phosphorylation state, which may affect signaling in epithelial wounds. CDCP1 acts as a marker for hematopoetic cells and also exhibits high expression in metastatic colon and breast tumors.
Application
|
Application |
Dilution Ratio |
|
WB |
1:500-1:1000 |
Overview
|
Immunogen |
Recombinant protein within Human CDCP1 aa 487-836 / 836 |
|
Species Reactivity |
Human, Mouse |
|
Validated Applications |
WB |
|
Molecular Weight |
Predicted band size: 93 kDa |
|
Positive Control |
SW480 cell lysate, HCT 116 cell lysate, NIH/3T3 cell lysate |
|
Conjugation |
unconjugated |
|
RRID |
AB_3068808 |
|
Form |
Liquid |
|
Concentration |
1ug/ul |
|
Storage Buffer |
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide |
|
Isotype |
IgG1 |
|
Purification Method |
Immunogen affinity purified |
Data
Western blot analysis of CDCP1 on different lysates with CD318 Mouse Monoclonal Antibody(ARA933) at 1/1,000 dilution.
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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